Brain Perfusion in Corticobasal Syndrome with Progressive Aphasia

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Brain Perfusion in Corticobasal Syndrome with Progressive Aphasia

BACKGROUND Brain perfusion may differ between patients with corticobasal syndrome (CBS) with and without aphasia. METHODS Twenty-six (9 males and 17 females; mean age 76 ± 5.3 years) patients with CBS were enrolled in the study. Brain MRI and single-photon emission computed tomography were performed in all subjects. Language was evaluated using the Standard Language Test of Aphasia. The patie...

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Rapidly Progressive Corticobasal Degeneration Syndrome

INTRODUCTION Corticobasal syndrome (CBS) has a heterogeneous clinical presentation with no specific pathologic substratum. Its accurate diagnosis is a challenge for neurologists; in order to establish CBS definitively, postmortem confirmation is required. Some clinical and radiological features can help to distinguish it from other neurodegenerative conditions, such as Creutzfeldt-Jakob disease...

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Primary progressive aphasia as the initial manifestation of corticobasal degeneration. A "three in one " syndrome?

In 1994, the term "Pick complex" was proposed to indicate significant clinical and pathological overlapping between primary progressive aphasia, frontal lobe dementia and corticobasal degeneration. We report the case of a 60-year-old man, who initially presented progressive non-fluent aphasia with orofacial apraxia, and subsequently, over a period of 3 years, developed mutism, pathological laug...

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Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations.

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ژورنال

عنوان ژورنال: Dementia and Geriatric Cognitive Disorders Extra

سال: 2016

ISSN: 1664-5464

DOI: 10.1159/000443329